Application and modification of methods for chromosome culture, preparation and analysis.
10.3760/cma.j.issn.1003-9406.2017.06.030
- Author:
Yan ZENG
1
Author Information
1. Genetic Laboratory, Shaoxing Women and Children's Health Care Hospital, Zhejiang 312000, China. Email: 2560336019@qq.com.
- Publication Type:Journal Article
- MeSH:
Cells, Cultured;
Chromosomes, Human;
Cytogenetic Analysis;
Humans;
Karyotyping;
Metaphase
- From:
Chinese Journal of Medical Genetics
2017;34(6):915-918
- CountryChina
- Language:Chinese
-
Abstract:
Chromosome analysis has been widely used in clinics including prenatal diagnosis. To obtain high-quality metaphase chromosomes, researchers have attempted to modify the methods for chromosome culture, preparation and analysis. Some large research centers also tried to establish standards for quality control. In this paper, modification of methods for the preparation of chromosomes in the last decade is reviewed.