Advance in clinical application of non-invasive prenatal screening using cell-free fetal DNA.
10.3760/cma.j.issn.1003-9406.2017.06.032
- Author:
Jilin HU
1
;
Baosheng ZHU
Author Information
1. Medical Faculty of Kunming University of Science and Technology, Kunming, Yunnan 650500, China. Email: bszhu@aliyun.com.
- Publication Type:Journal Article
- MeSH:
Cell-Free Nucleic Acids;
analysis;
DNA Copy Number Variations;
Female;
Humans;
Pregnancy;
Prenatal Diagnosis;
methods
- From:
Chinese Journal of Medical Genetics
2017;34(6):924-927
- CountryChina
- Language:Chinese
-
Abstract:
Non-invasive prenatal screening using cell-free fetal DNA (NIPS) has been integrated into the prenatal health care only in a short span of five years, and the guidelines provided by professional bodies have been continuously updated. The American College of Medical Genetics and Genomics has made a statement on NIPS in July, 2016, suggesting that the NIPS can replace conventional screening for Patau, Edwards and Down syndromes in a continuum of gestational age and for any maternal age, except those who are significantly obese. The scope of target diseases of NIPS are also growing. Meanwhile, pre- and post-test counseling for NIPS has put forward a greater challenge for medical professionals.
