New homoisoflavanones from Polygonatum odoratum (Mill.) Druce.
- Author:
Li-Hong LI
1
;
Feng-Zhi REN
;
Shu-Hong CHEN
;
Yue-Qi GAO
Author Information
1. Department of Natural Products, Drug Discovery of North China Pharmaceutical Company, Shijiazhuang 050015, China. llhong21@163.com
- Publication Type:Journal Article
- MeSH:
Isoflavones;
isolation & purification;
Molecular Structure;
Polygonatum;
chemistry
- From:
Acta Pharmaceutica Sinica
2009;44(7):764-767
- CountryChina
- Language:Chinese
-
Abstract:
To study chemical constituents of Polygonatum odoratum (Mill.) Druce, the compounds were separated with column chromatography and HPLC. On the basis of physicochemical properties and spectral data, their structures were confirmed. Nine compounds were isolated and identified as 5,7-dihydroxy-6-methoxyl-8-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (1), 5,7-dihydroxy-6-methyl-3-(2',4'-dihydroxybenzyl)chroman-4-one (2), 5,7-dihydroxy-6-methoxyl-8-methyl-3-(4'-methoxybenzyl)chroman-4-one (3), disporopsin (4), chrysoeriol (5), 5,4'-dihydroxy-7-methoxy-6-methylflavone (6), N-trans-feruloyltyramine (7), N-trans-feruloyloctopamine (8), and (+)-syringaresinol (9). Compounds 1-3 are new homoisoflavanones. Compounds 4-9 are isolated from this plant for the first time.
