Recent advances in the applications of ultrasonic microbubbles as gene or drug vectors.
- Author:
Yuan-Yuan SHEN
1
;
Zhong-Gao GAO
;
Natalya RAPOPORT
Author Information
1. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Drug Carriers;
Drug Delivery Systems;
Genetic Vectors;
Microbubbles;
Nanostructures;
Ultrasonics
- From:
Acta Pharmaceutica Sinica
2009;44(9):961-966
- CountryChina
- Language:Chinese
-
Abstract:
With the research and application of the new ultrasound microbubble contrast agents, ultrasonic microbubbles can not only help to image, but they can also be used as genes or drug carriers. The microbubbles as genes or drug carriers can pass across the endothelial cell barrier and release genes and drug under the action of ultrasound field, which achieve target treatment effect. Based on the relevant materials, the bioeffects, early successes with gene and drug delivery, and potential clinical applications are reviewed.
