Vascular endothelial progenitor cells and cytokines related to hematopoietic regulation--review.
- Author:
Pei-Hao ZHENG
1
;
You-Zhang HUANG
;
Ping-Di YANG
Author Information
1. The Postgroduate School of The Second Military Medical University, Shanghai 200433, China.
- Publication Type:Journal Article
- MeSH:
Cytokines;
physiology;
Endothelial Cells;
cytology;
Erythropoietin;
physiology;
Granulocyte Colony-Stimulating Factor;
physiology;
Granulocyte-Macrophage Colony-Stimulating Factor;
physiology;
Hematopoiesis;
physiology;
Humans;
Interleukin-18;
physiology;
Proteoglycans;
physiology;
Stem Cells;
cytology
- From:
Journal of Experimental Hematology
2005;13(5):918-920
- CountryChina
- Language:Chinese
-
Abstract:
Endothelial progenitor cell (EPC) is a subtype of progenitor cells that can circulate, proliferate and have the ability to differentiate into mature endothelial cells. Exploration of EPC have significance to understand the vascular forming process of adults physiologically and pathologically. Cytokines, especially haematopoiesis-related cytokines, cellular stimulating factors in the body also influence EPC. In this review, the advances of research on the relationship between EPC and some cytokines related with haematopoiesis (G-CSF, EPO, HAPO and IL-18) and the potential signal transduction pathway were summarised.