Advances in the endocrine factors affecting the development of gubernaculum testis.
- Author:
Wang-Dong DENG
1
;
Xue-Wu JIANG
Author Information
1. Department of Urology, First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China. dengwangdong@sina.com
- Publication Type:Journal Article
- MeSH:
Animals;
Calcitonin Gene-Related Peptide;
physiology;
Estrogens;
pharmacology;
Humans;
Insulin;
physiology;
Male;
Mice;
Proteins;
physiology;
Rats;
Testis;
drug effects;
embryology;
physiology
- From:
National Journal of Andrology
2006;12(5):446-449
- CountryChina
- Language:Chinese
-
Abstract:
The testicular gubernaculum plays an important role in testicular descent and development. Its differentiation and development are affected by many factors. Androgens, calcitonin gene-related peptide (CGRP), insulin-like factor 3 (INSL3), Müllerian inhibiting substance (MIS), epidermal growth factor (EGF) and environmental estrogens (EEs) are involved in gubernacular development. The effect of CGRP, INSL3 and especially EEs on genital system has been attracted more attention.
