OBJECTIVETo compare the therapeutic effect of traditional and modified apocrine gland removal surgery with the combination of high radiofrequency knife for axillary osmidrosis.

METHODS105 cases (210 sides) were randomly divided into traditional group A (38 cases, 76 sides) and modified group B (67 cases, 134 sides). The wound healing and complications were recorded. The clinical effect was followed up for 6-12 months after operation.

RESULTSNo flap necrosis happened in both groups. The cure rate was 82.89% (63/76)) and 92.54% (124/134) in group A and B, respectively, which was significantly different (P < 0.05). The effective rate of hair removal in group A and B was 42. 1%, 59. 7% (P < 0. 05). There is no markedly difference between the two groups in postoperative hematoma( P >0.05). The recurrence rate in group A and B was 9.21% and 1.49% respectively, with a statistically difference between them (P < 0.05).

CONCLUSIONSModified apocrine gland removal surgery with the combination of high radiofrequency knife can expose the apocrine gland better and the gland, as well as hair, can be removed in the most. The residue hair and recurrency of osmidrosis are very lower.