Investigation of anti acute inflammatory activity of beta-aminoceton which is derivative of anilin.
- Author:
Huong Tran Giang Nguyen
- Publication Type:Journal Article
- Keywords:
beta-aminoceton
- MeSH:
Anti-Inflammatory Agents;
analogs & derivatives
- From:Pharmaceutical Journal
1999;282(10):18-19
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Healthy rats with weight of 120-180 g were randomly divided into 4 groups. They tested the anti-acute inflamatory activity of T1 (3 -methoxy 4 hydroxy-5 bromobenzylidien para bromo anilin) and T2 (3-methoxy 4 hydroxy-5 nitrobenzylidien p-nitro anilin). The results have shown that T1 had a significant antiinflamatory activity after 2 h and 4 h of the test but had no antiflamatory activity after 6 h of the test comparing with the control. While the anti-inflamatory activity of T2 was not different from this in the control. This study concluded that the anti-inflamatory activity of derivatives of 5 bromo vanilin was better than this of derivatives of 5 -nitroanilin.
