Analysis on del detection of RhD (-) in unrelated blood donors.
- Author:
Li-Li BIE
1
;
Hong-Wei MA
;
Zan CHEN
;
Bo-Wei ZHANG
Author Information
1. Institute of Transfusion Medicine, Henan Provincial Red Cross Blood Center, Zhengzhou 450012, Henan Province, China. beilili@tom.com
- Publication Type:Journal Article
- MeSH:
Asian Continental Ancestry Group;
Blood Donors;
Humans;
Phenotype;
Rh-Hr Blood-Group System;
genetics;
immunology
- From:
Journal of Experimental Hematology
2009;17(4):1071-1073
- CountryChina
- Language:Chinese
-
Abstract:
The study was aimed to analyze Del phenotype of RhD (-) unrelated blood donors. RhD (-) was initially screened by routine serological test and confirmed by indirect antiglobulin test (IAT). Del phenotype was detected by hot-ether absorption-elution test. The results indicated that 106 RhD (-) samples were confirmed out of 38526 donors, and 28 cases were Del detected by hot-ether absorption-elution test. The incidence of Del in RhD (-) samples was 26.41%, The serological phenotypes of Del were Ccee (78.57%), CCee (14.29%) and CcEe (7.14%) respectively. In conclusion, the detection of Del by using hot-ether absorption-elution test is very important for reasonable application of RhD (-) blood. There is difference in Del phenotypes of populations in different regions of China and Japan.