Advances of study on immunophenotyping of myelodysplastic syndromes-review.
- Author:
Chun QIAO
1
;
Lei FAN
;
Yu-Jie WU
;
Jian-Yong LI
Author Information
1. Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province People Hospital, Nanjing 210029, Jiangsu Province, China.
- Publication Type:Journal Article
- MeSH:
Bone Marrow;
pathology;
Humans;
Immunophenotyping;
Karyotyping;
Myelodysplastic Syndromes;
genetics;
immunology;
pathology
- From:
Journal of Experimental Hematology
2009;17(4):1106-1110
- CountryChina
- Language:Chinese
-
Abstract:
The myelodysplastic syndromes (MDS) are a group of heterogeneous hematological disorders and characterized by abnormalities of bone marrow myeloblasts in morphology and count, ineffective hematopoiesis, decrease of peripheral blood cells and high risk of transforming into acute myeloid leukemia. In this review, the morphological examination of bone marrow, bone marrow biopsy, karyotyping analysis of chromosome, and the significance of flow cytometric immunophenotyping for diagnosis and prognosis of MDS patients are discussed.
