Effect of local anesthesia on pulpal blood flow in mechanically stimulated teeth.
10.5395/JKACD.2006.31.4.257
- Author:
Wan Sik CHU
1
;
Seung Ho PARK
;
Dong Kuk AHN
;
Sung Kyo KIM
Author Information
1. Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea. skykim@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Pulpal blood flow;
Epinephrine;
Lidocaine;
Cavity preparation;
Local anesthetics;
Neurogenic inflammation
- MeSH:
Anesthesia, General;
Anesthesia, Local*;
Anesthetics, Local;
Animals;
Cats;
Dental Enamel;
Dentin;
Epinephrine;
Flowmeters;
Flushing;
Lidocaine;
Neurogenic Inflammation;
Tooth*
- From:Journal of Korean Academy of Conservative Dentistry
2006;31(4):257-262
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aims of the study were to evaluate the effect of epinephrine-containing local anesthetics on pulpal blood flow (PBF) and to investigate its effect on cavity preparation-induced PBF change. PBF was recorded using a laser Doppler flowmeter (Perimed Co., Sweden) from canines of nine cats under general anesthesia before and after injection of local anesthetics and after cavity preparation. 2% lidocaine hydrochloride with 1 : 100,000 epinephrine was administered by local infiltration given apical to the mandibular canine at the vestibular area and the same volume of isotonic saline was injected on the contralateral tooth as a control. A round carbide bur was operated at slow speed with isotonic saline flushing to grind spherical cavities with increasing depth through the enamel and into the dentin on both teeth. The obtained data was analyzed with paired t-test. Cavity preparation caused significant increase of PBF (n = 9, p < 0.05). Local infiltration of lidocaine with epinephrine resulted in decreases of PBF (n = 9, p < 0.05), whereas there was no significant change of PBF with the physiologic saline as a control. Cavity preparation on tooth anesthetized with lidocaine with epinephrine caused significantly less increase of PBF than in control tooth (p < 0.05). Therefore, the result of the present study demonstrates that local infiltration of 2% lidocaine with 1 : 100,000 epinephrine effectively reduces PBF increase caused by cavity preparation.
