Use of for formula shine and Lal for screening the thalassemia.
- Author:
Nga Thi Hong Nguyen
- Publication Type:Journal Article
- Keywords:
Beta thalassemia
- MeSH:
Thalassemia;
diagnosis
- From:Journal of Vietnamese Medicine
2001;263(9):23-27
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Shine and Lal’s discrimination functions MCV2 x MCH x 0.01 was tested for its utility in diagnosing thalassemia trait. A2 and F determination on all samples with MCV2x MCHx0.01<1530. A value of more than 1530 rules out beta thalassemia trait. Ferritin quantitation were done on all samples to detect iron deficiency anemia. We have collected 103 samples with MCV2x MCHx0.01<1530. In this study, this method detected 91 cases as beta thalassemia trait (95%), 8 cases as HbE heterozygote, 1 case as iron deficiency anemia and 3 cases as normal.
