Clinical characteristics of adult acute myelogenous leukemia in National Institute of Hematology and Bloof Transfusion
- Author:
Phuong Minh Vu
;
Vinh Quang Pham
;
Khanh Quoc Bach
- Publication Type:Journal Article
- Keywords:
acute myelogenous leukemia;
acute leukemia
- MeSH:
Leukemia;
Myeloid;
Acute/ immunology;
Hematology
- From:Journal of Medical Research
2007;49(3):24-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: In Vietnam, there are increase rate of patients with acute leukemia including acute myelogenous leukemia. The clinical, gender, age as well as morphological characteristics of cells have prognostic significance about response to treatment and survival time of patients. Objectives: (1) To describe the distribution of acute myelogenous leukemia types by FAB standard in 'National Institute of Hematology and Blood Transfusion. (2) To describe the clinical characteristics of patients with acute myelogenous leukemia. Subjects and methods: The study included 67 patients diagnosed acute myelogenous leukemia by FAB standard without chemotherapy in 'National Institute of Hematology and Blood Transfusion. Results and conclusions: The median age: 35.55 \xb1 13.46, sex: 53% male, 47% female. Ratio of M0, M1, M2, M3, M4, M5, M6, M7 was 1, 10, 19, 18, 30, 13, 6, 1 %, respectively. 100% of these patients presented with anemia, 57 % with hemorrage, 46 % with fever. Lymphadenopathy was presented in 61 %, hepatomegaly was presented in 27% and spleenomegaly was presented in 9%. 53% of the patients had more bleeding was M3. Lymphadenopathy, hepatospleenomegaly had most frequently seen in the patients of M4 and M5 type. \r\n", u'\r\n', u'