1, 3-propanediol production under salt stress.
- Author:
Jiajie XU
1
;
Pengbo LIU
;
Chunping TAO
;
Cheng CHENG
;
Shuilin FU
;
Heng GONG
Author Information
1. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
- Publication Type:Journal Article
- MeSH:
Alcohol Dehydrogenase;
Alcohol Oxidoreductases;
metabolism;
Culture Media;
Culture Techniques;
Fermentation;
Glycerol;
metabolism;
Klebsiella pneumoniae;
growth & development;
metabolism;
physiology;
Propylene Glycols;
metabolism;
Sodium Chloride;
pharmacology;
Stress, Physiological
- From:
Chinese Journal of Biotechnology
2008;24(6):1098-1102
- CountryChina
- Language:Chinese
-
Abstract:
Through studying the process of glycerol fermentation to 1, 3-propanediol(1, 3-PD) by Klebsiella pneumoniae, it was found that the cell growth and product (or by-product) production were under salt stress. Cell growth and product formation kept high rate at low salt concentration. High salt concentration led to low growth of cells, final concentration of 1, 3-PD and conversion from glycerol to 1, 3-PD, and, 1, 3-propanediol oxidoreductase activity decreased. When the salt concentration in 5 m3 bioreactor was controlled under appropriate manner, the concentration of 1, 3-PD production was markedly enhanced. The final 1, 3-PD concentration ,the conversion of glycerol to 1, 3-PD and productivity were 64 g/L, 61% and 2.1 g/(L x h).
