Advances in the research of cell electrofusion under microgravity.
- Author:
Yan SUN
1
;
Yanhong YUAN
;
Zongchun YI
;
Fengyuan ZHUANG
;
Yubo FAN
Author Information
1. Department of Bioengineering, Beihang University , Beijing 100083, China. sunyan@buaa.edu.cn
- Publication Type:Journal Article
- MeSH:
Animals;
Cell Culture Techniques;
Cell Fusion;
methods;
Electric Stimulation;
Electroporation;
methods;
Mice;
Microelectrodes;
Weightlessness;
Weightlessness Simulation
- From:
Journal of Biomedical Engineering
2008;25(3):720-723
- CountryChina
- Language:Chinese
-
Abstract:
Bioseperation, cell cultivation and cell electrofusion are three main biological processes in space laboratories. Microgravity is free from the influences of convection and sedimentation. Therefore, it is an ideal realm for cell electrofusion and hence it can be used in the research of monoclonal antibody, cross breeding and microgravity biology. This paper reviews the research of cell electrofusion under microgravity, including the changes of cytoskeleton and the mechanism of cell electrofusion.
