Study on the modification surface material of heparinized polyurethane.
- Author:
Shuxian MENG
1
;
Xiaona WEN
;
Yaqing FENG
;
Hanqing GU
Author Information
1. School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
- Publication Type:Journal Article
- MeSH:
Blood Coagulation Tests;
Coated Materials, Biocompatible;
chemistry;
Heparin;
pharmacology;
Humans;
Materials Testing;
Partial Thromboplastin Time;
Polyurethanes;
chemical synthesis;
chemistry;
Surface Properties
- From:
Journal of Biomedical Engineering
2004;21(4):597-601
- CountryChina
- Language:Chinese
-
Abstract:
In this study cationic and heparinized polyurethanes (PUs) were synthesized by a two-step solution polymerized method. Cationic and heparinized PUs were investigated by infrared spectroscopy, electron spectroscopy for chemical analysis (ESCA) and turbidity method. At the same time, the PUs proved of good biocompatibility through the laboratory tests, including blood coagulation time (CT), activated partial thromb plastin time (APTT) and fibroblast culture. These materials have good biocompatible function.