Pathological development of researches on intervertebral disc degeneration.
- Author:
Liang FENG
1
;
Yueming SONG
Author Information
1. Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Biomechanical Phenomena;
Humans;
Intervertebral Disc;
pathology;
Intervertebral Disc Displacement;
etiology;
pathology
- From:
Journal of Biomedical Engineering
2004;21(5):867-870
- CountryChina
- Language:Chinese
-
Abstract:
This article reviews the literature about the etiology and pathology of intervertebral disc degeneration. The degeneration of intervertebral disc is associated with certain biomechanical factor. Stress can directly lead to the rupture of intervertebral disc and, more importantly, change its biological properties. And then, it can trigger the process of degeneration via inflammatory mechanism which may include autoimmunity.
