Effects of carbon phase components on platelets adhesion for diamond like carbon (DLC).
- Author:
Bogang LI
1
;
Jie YIN
;
Guangfu YIN
;
Juanjuan NA
;
Changqiong ZHENG
Author Information
1. College of Materials Science and Engineering, Sichuan University, Chengdu 610065, China.
- Publication Type:Journal Article
- MeSH:
Biocompatible Materials;
Carbon;
chemistry;
Diamond;
chemistry;
Humans;
Male;
Materials Testing;
Models, Biological;
Platelet Adhesiveness
- From:
Journal of Biomedical Engineering
2004;21(6):905-909
- CountryChina
- Language:Chinese
-
Abstract:
In the present paper, adhesive test, morphology observation, classified counting and deformation index calculation of the platelets on seven DLC samples made by different processes were carried out after XPS analysis, respectively. Then the effects of carbon phase components on amounts and deformation index of the platelets adhered to the samples were investigated by using the analysis of T-type correlation degree in the grey system theory. It has been shown from results that the amounts and the deformation index of the platelets adhered to the DLC samples made by plasma source ion implantation-ion beam enhanced deposition (PSII-IBED) are obviously less than those of DLC samples made by plasma CVD. The correlation degrees (negative) between the DLC carbon phase and the amounts as well as the deformation index of platelets are much more than those of the other four carbon phase components; besides, larger correlation degrees (positive) only appear between the deformation index of platelets and the C-H carbon phase or C-O carbon phase. It has been indicated that: (1) the effect of DLC carbon phase on platelets adhesion is much greater than that of the other four carbon phase components, the key to improvement in the hemocompatibility of DLC is to increase the DLC carbon phase content; (2) it is necessary to restrain the form or decrease the C-H carbon phase content and C-O carbon phase content so as to control their promotive action on deformation of the platelets adhered to the surface of DLC; (3) using PSII-IBED process to prepare DLC is helpful to improving the hemocompatibility of DLC. These conclusions are essential for designing and improving the deposition process of DLC.
