Biotransformation in vivo/vitro and bioactive properties of rare ginsenoside IH901.
- Author:
Yuxing TONG
1
;
Zhizhong ZHENG
;
Qingxuan TONG
;
Yi LIN
;
Yanlin MING
Author Information
1. College of Chemical Engineering, Huaqiao University, Xiamen 361021, Fujian, China.
- Publication Type:Journal Article
- MeSH:
Biotransformation;
Ginsenosides;
metabolism;
pharmacokinetics;
Humans;
Intestines;
metabolism;
microbiology;
Panax;
chemistry;
Sapogenins;
metabolism
- From:
Chinese Journal of Biotechnology
2012;28(6):684-695
- CountryChina
- Language:Chinese
-
Abstract:
Recent metabolomics research revealed a new ginseng ginsenoside IH901 that is synthesized by intestinal microbial transformation in oral administration of ginseng. IH901 shows various biological activities, including anti-tumor, anti-inflammatory, anti-diabetic, and anti-aging. In recent years, great effort has been made to prepare IH901 by microbial and enzymatic transformation in a large scale. In this paper, we reviewed the biotransformation pathways both in vivo and in vitro and bioactive properties of rare ginsenoside IH901.
