Comparison of changes in early pulmonary function and hemodynamic between unilateral and bilateral lung volume reduction for chronic obstructive pulmonary disease.
- Author:
Bin HU
1
;
Sheng-cai HOU
;
Hui LI
;
Tong LI
;
Yang WANG
;
Zhen-kui ZHANG
;
Jin-bai MIAO
;
Yi-li FU
;
Bin YOU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Hemodynamics; Humans; Intraoperative Period; Lung; physiopathology; Male; Middle Aged; Pneumonectomy; methods; Pulmonary Disease, Chronic Obstructive; physiopathology; surgery; Respiratory Function Tests; Time Factors
- From: Chinese Journal of Surgery 2007;45(8):552-554
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare changes in early pulmonary function and hemodynamics between unilateral and bilateral lung volume reduction (LVRS) for severe chronic obstructive pulmonary disease (COPD).
METHODSEighty-six patients with severe COPD underwent LVRS, 61 underwent unilateral LVRS and 25 underwent lateral LVRS. The results of lung function (FEV(1), RV, TLC), arterial blood gas analysis (PaO(2), PaCO(2)) and color Doppler echocardiography (CO, CI, EF, PAP) were evaluated preoperatively and 3, 6 months postoperatively.
RESULTSSix patients died. FEV(1), RV and TLC were improved significantly after (P < 0.05). PaO(2) increased (P < 0.05) and PaCO(2) decreased postoperatively (P < 0.05). According to the Doppler echocardiography there were no statistic difference in cardia functions (CO, CI, EF, PAP) between unilateral and bilateral LVRS preoperatively and 3, 6 months postoperatively.
CONCLUSIONSUnilateral and bilateral LVRS is safe and effective in the treatment of patients with severe COPD, the pulmonary function significantly improved postoperatively, but the results of bilateral LVRS is better than unilateral. Both unilateral and bilateral LVRS showed no significant deterioration in hemodynamics, there were no significant difference between preoperatively and postoperatively.
