Extramedullary plasmacytoma in the maxillary sinus.
- Author:
M A Megat SHIRAZ
1
;
Y H JONG
;
S H Primuharsa PUTRA
Author Information
1. Department of Otorhinolaryngology, Head & Neck Surgery, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.
- Publication Type:Case Reports
- MeSH:
Anemia;
complications;
Antineoplastic Agents;
therapeutic use;
Brain Neoplasms;
diagnosis;
pathology;
Fatal Outcome;
Humans;
Magnetic Resonance Imaging;
methods;
Male;
Maxillary Sinus;
diagnostic imaging;
pathology;
Maxillary Sinus Neoplasms;
diagnosis;
diagnostic imaging;
pathology;
Middle Aged;
Nasopharynx;
pathology;
Neoplasm Metastasis;
Plasmacytoma;
diagnosis;
diagnostic imaging;
pathology;
Radiography
- From:Singapore medical journal
2008;49(11):e310-1
- CountrySingapore
- Language:English
-
Abstract:
Extramedullary plasmacytoma is a rare malignant plasma cell tumour. We report an extremely aggressive case of extramedullary plasmacytoma of the right maxillary sinus, which had metastasised to the brain and rib. A 56-year-old man presented with recurrent epistaxis and acute anaemia. Nasendoscopy revealed a medialised medial wall of the right maxilla and a mass occupying the whole nasopharynx. Magnetic resonance imaging revealed a right maxillary tumour with extension to the ipsilateral nasal cavity, nasopharynx, right sphenoid and ethmoidal sinuses. There was an extra-axial brain metastasis. There were metastases to the right parietal region and left eighth rib. Histopathology examination of the maxillary mass revealed abundant plasma cells with kappa-chain restriction. He was planned for four cycles of chemotherapy. Unfortunately, in view of the advanced stage of disease, he succumbed to his disease during the first cycle of chemotherapy.
