Plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis.
- Author:
Xin-liang LU
1
;
Zheng-liang ZHANG
;
Jun-fu ZHOU
;
Jian-ting CAI
;
Ke-da QIAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Ascorbic Acid; blood; Female; Humans; Lipid Peroxides; blood; Liver Cirrhosis; blood; metabolism; Male; Middle Aged; Vitamin E; blood
- From: Journal of Zhejiang University. Medical sciences 2003;32(6):533-535
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis and to explore their significance.
METHODSThe plasma levels of ascorbic acid,vitamin E and lipoperoxides in patients with liver cirrhosis were measured, and the results were compared with those of sex-and age-matched healthy subjects.
RESULTThe plasma levels of ascorbic acid, vitamin E and lipoperoxides in the patients group were (42.94 +/-6.99)micromol/L, (17.99 +/-3.51)micromol/L and (14.09 +/-1.28)micromol/L, respectively, while those in the control group were (53.30 +/-9.45)micromol/L (t=9.50, P=0.000), (24.59 +/-7.22)micromol/L (t=7.94, P=0.000) and (12.11 +/-1.20)micromol/L (t=17.21, P=0.000), respectively.
CONCLUSIONThe levels of ascorbic acid and vitamin E in patients with liver cirrhosis decrease significantly,which may indicates the disturbance of balance between oxidation and antioxidation.
