Determination of luteolin and luteolin-7-beta-D-glucoside in Chrysanthemum morfolium Ramat. from different collection time by RP-HPLC.

Author: Bi-bo HU ¹ ; Hui-di JIANG ; Jun YANG ; Su ZENG
Author Information

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310031 China.
Publication Type:Journal Article
MeSH: Chromatography, High Pressure Liquid; Chrysanthemum; chemistry; Flavonoids; analysis; Glucosides; analysis; Luteolin
From: Journal of Zhejiang University. Medical sciences 2004;33(1):29-32
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo observe the content variation of luteolin and luteolin-7-beta-D-glucoside in Chrysanthemum morifolium Ramat. (CMR) from different collection time.
METHODSRP-HPLC was used to analyze these two components in CMR collected in 2001 and 2002.
RESULTThe content of luteolin was significantly lower than that of luteolin-7-beta-D-glucoside. Furthermore, the former showed no marked changes during collection, while the latter did not varied markedly in early collection but decreased significantly in later collection.
CONCLUSIONThe content of luteolin-7-beta-D-glucoside reflects the quality of Chrysanthemum morifolium Ramat. more viably than that of luteolin.