Comparison of single-dose nalbuphine versus tramadol for postoperative pain management in children: a randomized, controlled trial.
10.4097/kjae.2017.70.2.184
- Author:
Naeem LIAQAT
1
;
Sajid Hameed DAR
Author Information
1. Department of Pediatric Surgery, Services Institute of Medical Sciences/Services Hospital, Lahore, Pakistan. simsonian.chaudary@gmail.com
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Child;
Inguinal hernia;
Nalbuphine;
Postoperative pain;
Tramadol
- MeSH:
Analgesics;
Child*;
Hernia, Inguinal;
Humans;
Nalbuphine*;
Narcotics;
Pain, Postoperative*;
Postoperative Care;
Prospective Studies;
Tramadol*
- From:Korean Journal of Anesthesiology
2017;70(2):184-187
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Acute postoperative pain control in children is an essential component of postoperative care, particularly in daycare procedures. Giving patients continuous narcotic analgesics can be risky; however, a single dose may be sufficient. METHODS: This study used a prospective, randomized controlled design and was conducted at the Pediatric Surgery Unit, Services Hospital, Lahore. In total, 150 patients who underwent inguinal herniotomy (age range: 1–12 years) were randomly assigned to two groups: group A (nalbuphine) and group B (tramadol). Patients were given a single dose of either nalbuphine (0.2 mg/kg) or tramadol (2 mg/kg) immediately after surgery and pain was measured at 0, 1, 2, 4, and 8 h. RESULTS: The demographic characteristics were similar between the two groups. The mean pain score was lower in group A than in group B at 0 and 1 h (P < 0.05). However, at 4 h and 8 h, the pain scores in group A were still lower, but not significantly. In all, 9 patients (12.0%) required rescue analgesics in group A compared to 16 patients (21.3%) in group B (P = 0.051). The mean time for requirement of rescue analgesics was 6.5 ± 0.5 h in group A and 5.3 ± 1.7 h in group B (P = 0.06). CONCLUSIONS: A single dose of nalbuphine is sufficient, and superior to tramadol, for postoperative pain management in children who have undergone daycare procedures.
