Dynamic analysis of alkaloids and flavonoids in Genus Morus L. in China during different harvesting time.
- Author:
Li-li ZHANG
;
Yong-liang BAI
;
Shu-lan SU
;
Zhen OU-YANG
;
Li LIU
;
Sheng GUO
;
Da-wei QIAN
;
Jin-ao DUAN
- Publication Type:Journal Article
- MeSH:
Alkaloids;
analysis;
isolation & purification;
Chromatography, High Pressure Liquid;
Drug Stability;
Drugs, Chinese Herbal;
analysis;
isolation & purification;
Flavonoids;
analysis;
isolation & purification;
Mass Spectrometry;
Medicine, Chinese Traditional;
Morus;
chemistry;
Plant Leaves;
chemistry;
Plants, Medicinal;
Reproducibility of Results;
Seasons
- From:
China Journal of Chinese Materia Medica
2014;39(24):4822-4828
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the optimum harvesting time and utilization of mulberry leaves during different growth periods based on the content of alkaloids and flavonoids, 88 samples of 11 species of mulberry leaves were collected and analyzed. UPLC-TQ/MS method was applied and the results showed that the ingredients of alkaloids and flavonoids in mulberry leaves are quite different in different growth periods and different species. There was a sharp decline of the average content of alkaloids in all samples from October, while the content of flavonoids dropped either from October but with less volatile. The content of flavonoids in M. atropurpurea was much higher than alkaloids, while M. australis was opposite completely. There was a sharp decline of alkaloids in M. cathayana and M. mongolica from Tuly to August, however, the content of alkaloids and flavonoids in M. alba is neither too high nor too low. In summary, it is more suitable to harvest tender mulberry leaves harvested from the end of September to beginning of October that provide a scientific evidence for rational harvest and comprehensive utilization of mulberry leaves.