Advance in studies of Panax notoginseng saponins on pharmacological mechanism of nervous system disease.
- Author:
Ping SU
;
Lei WANG
;
Shi-Jing DU
;
Wen-Feng XIN
;
Wen-Sheng ZHANG
- Publication Type:Journal Article
- MeSH:
Animals;
Drugs, Chinese Herbal;
administration & dosage;
Gene Expression;
drug effects;
Humans;
Nervous System Diseases;
drug therapy;
genetics;
metabolism;
Panax notoginseng;
chemistry;
Saponins;
administration & dosage
- From:
China Journal of Chinese Materia Medica
2014;39(23):4516-4521
- CountryChina
- Language:Chinese
-
Abstract:
The pharmacological mechaisms of Panax notoginseng saponins on nervous system diseases (Alzheimer's disease, Parkinson's disease, ischermic cerebral apoplexy and depressive disorder) , including panax notoginseng saponins, protoparaxotriol saponins, panasadiol saponins, ginsenoside Rg1, ginsenoside Rb1, ginsenoside Re and notoginsenoside R1 were summarized to analyze the study hotspots and potential advantages (such as estrogen-like effect) of notoginsenoside's pharmacological actions, provide reference for further pharmacological studies and new ideas for clinical treatment of nervous system diseases and drug studies and development.
