Advance of researches in nitric oxide biological function on wound repair.
- Author:
Xinyan TANG
1
;
Li YANG
;
K L Paul SUNG
Author Information
1. Bioengineering College, Chongqing University, Chongqing 400044, China. tangxinyancqu@126.com
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Neovascularization, Physiologic;
Nitric Oxide;
metabolism;
physiology;
therapeutic use;
Wound Healing;
drug effects;
physiology
- From:
Journal of Biomedical Engineering
2010;27(1):211-214
- CountryChina
- Language:Chinese
-
Abstract:
Nitric oxide (NO) is a short-life free radical that acts as the small biological molecule, and exists in body extensively. Since its discovery over 20 years ago, NO has been found to play an important regulation role in angiogenesis, nerve and immune system. The subsequent studies also showed that NO exerted an important biological action in wound repairing and healing, which involved in the following phases of wound repair, inflammation, cell proliferation, matrix deposition and remodeling. This paper reviews recent findings from in vitro & in vivo studies of NO in wound repair, and the biological function and mechanisms of NO in wound repair.
