Adipocytokines: factors with various suggested functions.
- Author:
Ye ZHU
1
;
Dejia HUANG
Author Information
1. Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Adipokines;
physiology;
Adiponectin;
physiology;
Adipose Tissue;
chemistry;
physiology;
Humans;
Leptin;
physiology;
Resistin;
physiology
- From:
Journal of Biomedical Engineering
2010;27(2):476-480
- CountryChina
- Language:Chinese
-
Abstract:
Fat accumulation has been shown to play important roles in the development of obesity-related disorders such as atherosclerosis, diabetes mellitus and hypertension. Recent studies have shown that fat tissue is not a simple energy storage organ, but exerts important endocrine functions. These are achieved predominantly through release of adipocytokines, which include several novel molecules released by adipocytes like leptin, resistin, adiponectin or visfatin, as well as some more classical cytokines released possibly by inflammatory cells, like TNF-alpha and IL-6. Adipocytokines may affect cardiovascular, hepatic, muscular and metabolic function. In this review, the recent research work of adipocytokines will be discussed.