Magnetic resonance image of sellar region in pituitary stalk interruption syndrome in children and adolescents.
- Author:
Pan Qi WEI
1
;
Zhu Hui JUAN
;
Gong Feng YING
;
Li Nai SHI
;
Zhang TAO
;
Bai GANG
;
Pan HUI
;
Zeng XIAN-WEI
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Child; Female; Humans; Hypopituitarism; diagnosis; pathology; Magnetic Resonance Imaging; Male; Pituitary Gland; pathology; Retrospective Studies; Sella Turcica; pathology; Young Adult
- From: Acta Academiae Medicinae Sinicae 2011;33(1):9-13
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate the magnetic resonance imaging (MRI) manifestations of sellar region of children and adolescents with pituitary stalk interruption syndrome (PSIS).
METHODSThirty-one PSIS cases were selected from February 2001 to August 2010 in Peking Union Medical College Hospital. MRI images were collected to calculate the volume and coronary area of the pituitary based on its measured height, width, and anteroposterior diameter. The results of the measurement were retrospectively analyzed together with clinical data.
RESULTSThe patients in this study included 28 males and 3 females, aged 16.5∓3.8 years (range, 6~25 years). MRI images showed pituitary stalk rupture associated with ectopic posterior pituitary in 16 cases, significantly thinner or unclear pituitary stalk in 15 cases, in which 7 cases were found with vacuole turcica. All the 31 patients presented with reduced pituitary volume and dysfunction of anterior pituitary.
CONCLUSIONPSIS may show pituitary stalk interruption with ectopic posterior, thinning or unclear of pituitary stalk, and with a variety of anterior pituitary hormone deficiency.
