Research advances in induced pluripotent stem cells.
10.3881/j.issn.1000-503X.2011.04.022
- Author:
Xing-ran JIANG
1
;
Shi-xin LU
Author Information
1. State Key Laboratory of Molecular Oncology, Cancer Institute & Hospital, CAMS and PUMC, Beijing, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Induced Pluripotent Stem Cells
- From:
Acta Academiae Medicinae Sinicae
2011;33(4):456-461
- CountryChina
- Language:Chinese
-
Abstract:
Differentiated somatic cells can be directly reprogrammed into induced pluripotent stem (iPS) cells in vitro. Similarly to embryonic stem (ES) cells, iPS cells have pluripotency to differentiate into all cell types and capability to self-renew themselves indefinitely. Without immune rejection and ethical issues, patient-specific iPS cells promise to be an ideal tool for regenerative medicine, drug screening, and toxicity testing.
