Clinical characteristics and outcome comparison between young (≤ 45 years) female and male patients with coronary artery disease undergoing percutaneous coronary intervention
10.3760/cma.j.issn.0253-3758.2010.03.010
- VernacularTitle:45岁以下行冠状动脉介入治疗女性冠心病患者的临床特点
- Author:
Jing-Han HUANG
1
;
Shu-Bin QIAO
;
Bo XU
;
Jian-Jun LI
;
Jue CHEN
;
Hai-Bo LIU
;
Yue-Jin YANG
;
Min YAO
;
Yong-Jian WU
;
Jin-Qing YUAN
;
Xue-Wen QIN
;
Yuan WU
;
Jun DAI
;
Shi-Jie YOU
;
Feng-Huan HU
;
Wei-Hua MA
;
Jie QIAN
;
Pei ZHANG
;
Ke-Fei DOU
;
Ji-Lin CHEN
;
Zai-Jia CHEN
;
Run-Lin GAO
Author Information
1. 中国医学科学院,北京协和医学院,阜外心血管病医院
- Keywords:
Coronary disease;
Angioplasty,transluminal,percutaneous coronary;
Female
- From:
Chinese Journal of Cardiology
2010;38(3):248-251
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical characteristics and clinical outcomes in young (≤45 years) female and male coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI). Methods Angiographic and clinical data from 124 premenopausal female patients who underwent elective PCI from April 2004 to February 2008 were compared to age-matched 430 male patients who underwent elective PCI between 2006 and 2007 in our department. All patients were treated according to guidelines and coronary angiography was repeated after 6 months. One year clinical follow-up were performed in all patients. Results Incidences of dyslipidemia, the history of myocardial infarction and smoking were significantly lower in female patients than in male patients (all P < 0.01 ). Left main, left anterior descending and bifurcation lesions were more common while type C lesion and right coronary lesion were less common in young female CAD group compared to young male CAD group (P <0. 01 -0. 05). The average lesion length in female patients was significantly longer than that in male patients [ (20. 36±13.37)mm vs.( 23.04±13.86) mm, P < 0. 05 ]. The in-hospital and follow-up incidences of major adverse cardiac events,stent thrombosis and in-stent restenosis were similar between young female and male CAD patients.Conclusions CAD risk factors were less and vessel lesions were more likely to be found at left main, left anterior descending and bifurcation in young female CAD patients compared to young male CAD patients.The clinical outcomes were similar between young female and male CAD patients.
