Outcome of transcatheter closure of perimembranous ventricular septal defect with modified double-disk occluder device
10.3760/cma.j.issn.0253-3758.2010.04.011
- VernacularTitle:国产封堵器治疗先天性膜周部室间隔缺损的疗效评估
- Author:
Jing LIU
1
;
Xiao-Hua YOU
;
Xian-Xian ZHAO
;
Jian-Qiang HU
;
Jiang CAO
;
Rong-Liang XU
;
Hong WU
;
Shao-Ping CHEN
;
Jian-Liang ZHANG
;
Xing ZHENG
;
Yong-Wen QIN
Author Information
1. 第二军医大学附属长海医院
- Keywords:
Ventricular septal defect;
Heart catheterization;
Occluder device
- From:
Chinese Journal of Cardiology
2010;38(4):321-325
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and adverse effects of transcatheter closure of perimembranous ventricular septal defect (pmVSD) with modified double-disk occluder device (MDVO).Methods Clinical data including clinical examination,electrocardiography daily after the procedure for a week,chest-X-rays and TIE before discharge and at 3-5 days after the procedure were analyzed from 604 patients underwent percutaneous closure of a pmVSD with MDVO at our department between December 2001 and December 2008.Results Procedure was successful in 576 out of 604 patients (95.4%) and 583 VSD occtuders were placed.Endocarditis,thromboembolism,or deaths were not observed after procedure.Conduction block occurred in 81 patients (56 RBBB,14 LBBB) and transient nonparoxysmal ventricular tachyeardia in 31 patients after the procedure.Complete heart block occurred in 11 patients,9 of them recovered in 3 weeks,permanent pacemaker was implanted in 2 patients (one had transient Ⅲ°AVB before the procedure,the other underwent simultaneous closure of ventricular septal defect and atrial septal defect).Trivial/small residual shunts were found in 69 patients(12.0%).The residual shunts disappeared in 31 patients and remained unchanged in 38 patients (6.6%) 7 days after procedures.Aortic regurgitation developed in 5 patients (2 trivial/small,3 small/moderate),and tricuspid regurgitation was present in 35 patients (32 trivial/small,3 moderate).Five patients developed haemolysis (device retrieved via catheter in 1 patient due to persistent haemolysis,the other 4 patients recovered 3-14 days post procedure) .Pseudoaneurysm of femoral artery occurred in 1 patient,and disappeared by pressure dressing.Device was successfully replaced in 2 patients with either device embolization (n = 1) or device misplacement (n = 1)after device retrieval by catheter.Conclusion It is safe and effective to close congenital perimembranous ventricular septal defect with domestic-made occluder device.
