Pathology of myocardial fatty infiltration :an autopsy report from 117 cases
10.3760/cma.j.issn.0253-3758.2010.04.018
- VernacularTitle:非心律失常性右心室心肌病心肌脂肪浸润117例尸检病理分析
- Author:
Bo-Tao LUO
1
;
Han-Guo JIANG
;
Ying-Hai ZHAO
;
Xiao-Yi CHEN
Author Information
1. 广东医学院
- Keywords:
Myocardium;
Adipose tissue;
Pathology
- From:
Chinese Journal of Cardiology
2010;38(4):350-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors related to the formation of myocardial fatty infiltration and possible pathological consequences.Methods The macroscopic and microscopic findings in 117 autopsy cases with myocardial fatty infiltration were examined during October,2001 to June,2009.Results There was a significant positive correlation between the macroscopic grading of subepicardial adipose tissue and the microscopic myocardial fatty infiltrative degree(r_s=0.57,P ＜0.01)but there was no correlations between the myocardial fatty infiltrative degree and age as well as coronary arteriosclerosis (all P ＞0.05).The percent of myocardial atrophy was 39.32% (46/117),and the rate of myocardial atrophy in mild myocardial fatty infiltration group (13/63,20.63%) was significantly lower than that in moderate myocardial fatty infiltration group(22/39,34.92%;χ~2= 12.14,P ＜0.01) and in severe myocardial fatty infiltration group(11/15,73.33%;χ~2 = 13.42 ,P ＜0.01).There were 28 sudden cardiac deaths among the 117 eases including 6 deaths due to myocardial fatty infiltration.Conclusions Myocardial fatty infiltration is often associated with myocardial atrophy,even with sudden cardiac death but is not an accompanying pathologic changes of aging and coronary arteriosclerosis.
