Paget's Disease is Associated with Eleven Cancerous Regions: a Case Report and Therapeutic Strategy
10.1007/s11596-009-0529-y
- Author:
SONG YONGXI
1
;
WANG ZHENNING
;
XU HUIMIAN
;
YUE ZHENYU
;
XING CHENGZHONG
Author Information
1. Department of Surgical Oncology and General Surgery, the First Hospital of China Medical University, Shenyang 110001, China
- Keywords:
Paget's disease;
multifocal and multicentric breast carcinoma;
modified radical mastectomy
- From:
Journal of Huazhong University of Science and Technology (Medical Sciences)
2009;29(5):677-678
- CountryChina
- Language:Chinese
-
Abstract:
Paget's disease of the breast is an uncommon disorder that accounts for 1% to 3% of all mammary tumors. The incidence of underlying carcinoma associated with Paget's disease has been re-ported in 82% to 100% of cases. The finding of underlying carcinoma reaches almost 100% when a palpable lump is also present. In this rare case, we described a patient presenting with Paget's disease but no palpable lump. However, we found 11 independent regions which were all invasive ductal carci-noma after the operation. Considering this patient, we should pay more attention to a multifocal and multicentric breast carcinoma associated with Paget's disease. Furthermore, we believe the mammog-raphy examination and a modified radical mastectomy are the most appropriate treatments for this population in clinical practice.
