Incidence and risk factors of HIV infection among sero-negative spouses of HIV patients in Dehong prefecture of Yunnan province.
- Author:
Song DUAN
1
;
Yue-cheng YANG
;
Li-fen XIANG
;
Run-hua YE
;
Man-hong JIA
;
Hong-bing LUO
;
Yu-xian ZHAO
;
Da REN
;
Yong-cheng PU
;
Wen-xiang HAN
;
Zhong-ju YANG
;
Wei-mei LI
;
Ji-bao WANG
;
Yan-ling LI
;
Jin YANG
;
Zhuo-hua FU
;
Na HE
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; China; epidemiology; Female; HIV Infections; epidemiology; HIV Seronegativity; Humans; Incidence; Male; Middle Aged; Prospective Studies; Risk Factors; Sexual Behavior; Spouses; Young Adult
- From: Chinese Journal of Epidemiology 2010;31(9):997-1000
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the HIV incidence and risk factors among sero-negative spouses of HIV patients in Dehong prefecture of Yunnan province.
METHODSA cohort of sero-negative spouses of the HIV patients had been developed and followed up since November, 2005. HIV new infections and related behaviors had been investigated every six months.
RESULTSBy the end of June, 2008, 790 sero-negative spouses of HIV patients had been recruited, of whom 702 were followed-up for at least one time. During the total 1202.35 person-years, 31 new HIV infections were identified, with an overall incidence of 2.58/100 person-years. The HIV incidence rates were 2.22/100 person-years in 2006, 2.95/100 person-years in 2007 and 2.74/100 person-years in 2008. Data from the Cox proportional hazard regression model indicated that those who resided in Yingjiang county [hazard ratio (HR) = 4.37, 95%CI: 1.48 - 12.90, P = 0.008], ever using drugs (HR = 3.49, 95%CI: 1.09 - 11.18, P = 0.035), or having an HIV-infected spouse who never exposed to antiretroviral treatment (HR = 3.60, 95%CI: 1.41 - 9.16, P = 0.007) were at higher risk for HIV infection.
CONCLUSIONSero-negative spouses of HIV patients in Dehong prefecture of Yunnan province had a relatively high incidence of HIV new infection during 2006-2008. More efforts should put on those people living in these areas, having a history of drug use or having an HIV-infected spouse who had never been exposed to antiretroviral treatment.
