Study on the cytocompatibility of biodegradable poly(epsilon-caprolactone) microspheres in vitro.
- Author:
Qizhi LUO
1
;
Jianhai CHEN
;
Kaijin DAI
Author Information
1. Central Laboratory, First Military Medical University, Guangzhou 510515.
- Publication Type:Journal Article
- MeSH:
Animals;
Biocompatible Materials;
chemical synthesis;
pharmacology;
Biodegradation, Environmental;
In Vitro Techniques;
Materials Testing;
Mice;
Microspheres;
Polyesters;
chemical synthesis;
pharmacology
- From:
Journal of Biomedical Engineering
2003;20(1):14-16
- CountryChina
- Language:Chinese
-
Abstract:
Poly(epsilon-caprolactone) microspheres were fabricated with an average particle size of 5.08 +/- 0.23 microns. The effect of poly(epsilon-caprolactone) microspheres on apoptosis and cell cycle of fibroblast was studied with flow cytometry. The data obtained clearly indicated that poly(epsilon-caprolactone) microspheres purified in different ways showed different cytocompatibility. The well purified microspheres have good cytocompatibility.
