OBJECTIVETo study the distribution and drug resistance of pathogenic bacterium and find the proper measures of infection control.

METHODSSix hundred and eighty-two pathogenic bacteria strains were isolated and cultured from samples collected from January 2003 to December 2005. The pathogenic bacterium distribution and antibiotic resistance were analyzed.

RESULTSThe detection rate of gram-negative bacteria was higher than gram-positive ones. The gram-positive bacteria accounted for 292 strains (42.8%), in which the detection rate of staphylococcus aureus is highest (16.7% of total) and the detection rate of methicillin-resistant staphylococcus aureus accounted for 82.5% in staphylococcus aureus strains. Among 372 gram-negative bacteria strains (54.5%), the detection rate of bacillus aeruginosa, escherichia coli, baumannii and enterobacter cloacae were 12.5%, 11.1%, 9.1% and 8.2% respectively; extended-spectrum beta-lactamases (ESBLs) were detected in 45 (60.8%) escherichia coli and 9 (42.9%) klebsiella pneumoniae strains. Eighteen strains of fungus were found, and it decreased in last 2 years. The detection rate of opportunistic pathogenic bacteria and the antibiotic resistant strains kept increasing in the 3 years.

CONCLUSIONSDrug resistance of pathogenic bacterium is very serious in burns department. The irrational use of broad-spectrum antibiotics and the antibiotic detection of pathogenic bacterium are all contributed to the drug resistance. It is important to enhance the asepsis, prevent hospital infection, detect the pathogenic bacteria and use antibiotics rationally in burns department.