Adult living donor liver transplantation using right lobe for severe hepatitis in emergency: a report of 9 cases.
- Author:
Feng ZHANG
1
;
Xue-Hao WANG
;
Xiang-Cheng LI
;
Lian-Bao KONG
;
Bei-Cheng SUN
;
Guo-Qiang LI
;
Xiao-Feng QIAN
;
Feng CHENG
;
Sen LU
;
Ling LÜ
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Critical Illness; Emergency Medical Services; Female; Follow-Up Studies; Hepatitis; pathology; surgery; Humans; Liver Transplantation; methods; Living Donors; Male; Middle Aged; Retrospective Studies; Treatment Outcome
- From: Chinese Journal of Surgery 2007;45(15):1019-1022
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the outcome of emergency adult right lobe living donor liver transplantation for fulminant hepatitis.
METHODSNine cases of adult right lobe living donor liver transplantation were performed from September 2002 to August 2005, the clinical and follow-up data was analyzed.
RESULTSAccording to Child Pugh Turcotte (CPT) classification, 9 patients were classified as grade C before transplant. The Model for End-Stage Liver Disease (MELD) scores of these patients were 26.7 +/- 8.8. The principal pre-transplant complications included hepatic encephalopathy (5 cases), electrolyte disturbance (3 cases), renal failure (2 cases), gastrointestinal bleeding (1 case). The operations in donors and recipients were all successful. The post-transplant complications induced pulmonary infection in 2 patients, acute renal failure in 3 and transplantation related encephalopathy in 1. There were no primary graft non-function and no blood vessel and bile tract complications occurred. One-year survival rate was 55.6%. No serious complication or death found in donors.
CONCLUSIONSEmergency adult to adult living donor liver transplantation is an effective treatment for fulminant hepatitis but the safety of the donors should be assessed strictly preoperation.