Clinical analysis of therapeutic effects of sphincter-preserving operation and Miles operation for rectal cancer.
- Author:
Fu-yi ZUO
1
;
Shi-yong LI
;
Bo YU
;
Zhen-jia LIANG
;
Shu-jun YUAN
;
Gang CHEN
;
Guang CHEN
;
Xue BAI
;
Xiao-jun WEI
;
En WU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Anal Canal; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Quality of Life; Rectal Neoplasms; mortality; surgery; Retrospective Studies; Surgical Procedures, Operative; methods; Survival Rate; Treatment Outcome
- From: Chinese Journal of Surgery 2007;45(17):1176-1178
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate and compare therapeutic effects of sphincter-preserving operation and Miles operation for rectal cancer.
METHODSA retrospective analysis was carried out in 572 cases of rectal cancer operations performed from January 1980 to December 2006.
RESULTSSphincter-preserving operation was carried out in 403 cases and Miles procedure in 169 cases. The follow-up rate was 76.2% (436/572) with a period of 0.5 - 25.0 years (median, 9.5 years). Local recurrence occurred in 6.3% (20/317) of sphincter-preserving operation and 7.6% (9/119) of Miles operation, the differences was not significant (chi2 = 1.3942, P > 0.05). Distal metastasis was found in 50 cases (15.7%) of sphincter-preserving operation and 19 cases (16.2%) of the Miles operation with no significant difference (chi2 = 0.6672, P > 0.05). There was no significant difference in five-year survival rate between the two groups, with 67.8% in sphincter-preserving operation and 67.2% in Miles operation.
CONCLUSIONSSphincter-preserving operations can improve the quality of life in rectal cancer although with the same five-year survival rate and recurrence rate as Miles operation. The operation for rectal cancer should be performed individually according to the location, the bionomics and the clinical stage.
