Imaging diagnosis of small hepatocellular carcinoma using ultrasound, contrast-enhanced ultrasound and multislice spiral CT.
- Author:
Lin DAI
1
;
Xiao-rong FENG
;
Yong-peng CHEN
;
Wei-qun WEN
;
Yi-kai XU
Author Information
- Publication Type:Journal Article
- MeSH: Carcinoma, Hepatocellular; diagnosis; Contrast Media; administration & dosage; Female; Humans; Image Enhancement; methods; Liver; diagnostic imaging; Liver Neoplasms; diagnosis; Male; Reproducibility of Results; Sensitivity and Specificity; Tomography, Spiral Computed; methods; Ultrasonography, Doppler, Color; methods
- From: Journal of Southern Medical University 2008;28(8):1469-1471
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the value of gray-scale ultrasound, contrast-enhanced ultrasound and multislice spiral CT in early and differential imaging diagnosis of small hepatocellular carcinoma (SHCC).
METHODSThis study included 35 patients with space-occupying lesions in the liver identified by routine ultrasound examination. The hemodynamics of the patients was recorded during the arterial, portal and lag phases using contrast-enhanced ultrasound. The enhancement features of the 3 phases were observed using multislice spiral CT. All the cases were confirmed by pathological examinations.
RESULTSFor SHCC diagnosis, gray-scale ultrasound, contrast-enhanced ultrasound and multislice spiral CT showed a sensitivity of 77.8%, 94.4%, and 100%, specificity of 88.2%, 100%, and 94.1%, positive predictive value of 87.5%, 100%, and 94.7%, negative predictive values 78.9%, 94.4%, and 100%, concordance rate of 82.9%, 97.1%, and 97.1% and Younden index of 0.66, 0.94, and 0.94, respectively.
CONCLUSIONSContrast-enhanced ultrasound and multislice spiral CT have significantly greater diagnostic efficacy than gray-scale ultrasound in early and differential diagnosis of SHCC. But in some atypical cases, gray-scale ultrasound, contrast-enhanced ultrasound and multislice CT have to be combined to establish a diagnosis.
