The role of research in transplantation.
- Author:
Roy Y CALNE
1
Author Information
1. University of Cambridge, Cambridge, UK. calne@hermes.cam.ac.uk
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Cyclosporine;
pharmacology;
Graft Rejection;
drug therapy;
prevention & control;
Humans;
Immunosuppression;
Immunosuppressive Agents;
pharmacology;
Transplants;
ethics
- From:Annals of the Academy of Medicine, Singapore
2009;38(4):354-355
- CountrySingapore
- Language:English
-
Abstract:
In the past 50 years, organ transplantation has developed from an improbable laboratory exercise to a major therapeutic success. The surgical problems of organ grafting have, for the most part, been solved. Rejection of grafts is now partially understood and usually controllable by powerful immunosuppressive drugs. A steady improvement in patient outcome, especially following the introduction of cyclosporin as an immunosuppressive agent has resulted in a worldwide shortage of organs for transplantation. This has provoked serious ethical dilemmas in every country. These matters are summarised in the following text.
