Long-Term Outcome and Surveillance Colonoscopy after Successful Endoscopic Treatment of Large Sessile Colorectal Polyps.
10.3349/ymj.2016.57.5.1106
- Author:
Bun KIM
1
;
A Ra CHOI
;
Soo Jung PARK
;
Jae Hee CHEON
;
Tae Il KIM
;
Won Ho KIM
;
Sung Pil HONG
Author Information
1. Department of Medicine, Graduate School, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Colorectal neoplasm;
gastrointestinal endoscopy;
colonoscopy
- MeSH:
Adult;
Aged;
Colonic Neoplasms/*diagnosis/pathology/surgery;
Colonic Polyps/*diagnosis/pathology/surgery;
*Colonoscopy;
Endoscopic Mucosal Resection;
Female;
Humans;
Male;
Middle Aged;
Neoplasm Recurrence, Local/*diagnosis;
Prospective Studies;
Time Factors;
Watchful Waiting/*methods
- From:Yonsei Medical Journal
2016;57(5):1106-1114
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Although there is a consensus about the need for surveillance colonoscopy after endoscopic resection, the interval remains controversial for large sessile colorectal polyps. The aim of this study was to evaluate the long-term outcome and the adequate surveillance colonoscopy interval required for sessile and flat colorectal polyps larger than 20 mm. MATERIALS AND METHODS: A total of 204 patients with large sessile and flat polyps who received endoscopic treatment from May 2005 to November 2011 in a tertiary referral center were included. RESULTS: The mean age was 65.1 years and 62.7% of the patients were male. The mean follow-up duration was 44.2 months and the median tumor size was 25 mm. One hundred and ten patients (53.9%) received a short interval surveillance colonoscopy (median interval of 6.3 months with range of 1-11 months) and 94 patients (46.1%) received a long interval surveillance colonoscopy (median interval of 13.6 months with range of 12-66 months). There were 14 patients (6.9%) who had local recurrence at the surveillance colonoscopy. Using multivariate regression analysis, a polyp size greater than 40 mm was shown to be independent risk factor for local recurrence. However, piecemeal resection and surveillance colonoscopy interval did not significantly influence local recurrence. CONCLUSION: Endoscopic treatment of large sessile colorectal polyps shows a favorable long-term outcome. Further prospective study is mandatory to define an adequate interval of surveillance colonoscopy.