Systemic lupus erythematosus and immune-inflammatory thrombophilia.
10.7534/j.issn.1009-2137.2014.05.061
- Author:
Zou LI
1
;
Jian GU
2
Author Information
1. Clinical Medical College of Yangzhou University, Yangzhou Institute of Hematology, Yangzhou 225001, Jiangsu Province, China.
2. Clinical Medical College of Yangzhou University, Yangzhou Institute of Hematology, Yangzhou 225001, Jiangsu Province, China. E-mail: maolujiu918@163.com.
- Publication Type:Journal Article
- MeSH:
Blood Coagulation;
Blood Coagulation Factors;
Humans;
Lupus Erythematosus, Systemic;
immunology;
Thrombophilia;
immunology;
Thrombosis
- From:
Journal of Experimental Hematology
2014;22(5):1499-1502
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease with causes including activation of innate and adaptive immune systems. SLE patients are with a high risk of thrombosis, which may be due to disease activation, immune complexes, toxic antibodies and high level of inflammation. This article discusses neutrophil/NET factor, antibody factor, platelet factor and particle factor which is involved in coagulation pathways and thrombus formation mechanism under the state of immune disorders in SLE.
