Blood matching and transfusion for 12 acute autoimmune hemolytic anemia patients by extracorporal hemolysis test.
10.7534/j.issn.1009-2137.2014.06.040
- Author:
Min YUAN
1
;
Cong-Hai TANG
1
;
A-Yang WU
1
;
Hui-Cong YANG
1
;
Wei-Wei GAN
1
;
Tian-Xin ZHANG
1
;
Yan-Xue HUANG
1
;
Wei-Ping XU
2
Author Information
1. Department of Blood Transfusion, Zhangzhou Hospital Affiliated to Fujian Medical University, Zhangzhou 363000, Fujian Province, China.
2. Department of Blood Transfusion, Southest Hospital Affiliated to Xiamen University,zhangzhou 363000, Fujian Province, China. E-mail:zz175xwp@163.com.
- Publication Type:Journal Article
- MeSH:
Anemia, Hemolytic, Autoimmune;
therapy;
Blood Transfusion;
Coombs Test;
Erythrocyte Count;
Erythrocytes;
Hemolysis;
Humans;
Platelet Transfusion
- From:
Journal of Experimental Hematology
2014;22(6):1716-1720
- CountryChina
- Language:Chinese
-
Abstract:
In order to screen the compatible red cells by using extracorporal hemolysis test for acute autoimmune hemolytic anemia (AIHA) patients who were difficult to be matched by automatic microcolumn gel indirect antiglobulin test. Twenty-six cases of AIHA were chosen as control group, to whom the same type of donor red blood cells were infused with the weakest blood agglutination; 12 cases of acute AIHA patients were chosen as test group, these patients were difficult to be matched by automatic microcolumn gel indirect antiglobulin test, and the donor red cells without hemolysis by extracoral hemolysis test were transfused for them. The results showed that compared with the control group,the effect of transfusion was better in test group (P < 0.01), with 2.26 U leukocyte-depleted erythrocyte suspension in average, whose hemoglobin, reticulocyte and total bilirubin levels were changed significantly compared with those before blood transfusion (P < 0.01) . It is concluded that the compatible red blood cells for the acute AIHA patients can be screened by the extracorporal hemolysis test, when it is difficult to screen by the automatic microcolumn gel indirect antiglobulin test.
