High Shear Stress at the Surface of Enhancing Plaque in the Systolic Phase is Related to the Symptom Presentation of Severe M1 Stenosis.
10.3348/kjr.2011.12.4.515
- Author:
Dae Chul SUH
1
;
Sung Tae PARK
;
Tack Sun OH
;
Sang Ok PARK
;
Ok Kyun LIM
;
Soonchan PARK
;
Chang Woo RYU
;
Deok Hee LEE
;
Young Bae KO
;
Sang Wook LEE
;
Kyunghwan YOON
;
Jong Sung KIM
Author Information
1. Department of Radiology and the Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul 138-736, Korea. dcsuh@amc.seoul.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Cerebral artery;
Atherosclerosis;
MRI, Plaque rupture, Fluid structure interaction
- MeSH:
Blood Flow Velocity;
*Cerebral Angiography;
Cerebrovascular Circulation;
Computational Biology;
Humans;
Image Interpretation, Computer-Assisted;
Imaging, Three-Dimensional;
Intracranial Arteriosclerosis/*diagnosis;
*Magnetic Resonance Angiography;
Shear Strength;
Software;
Systole
- From:Korean Journal of Radiology
2011;12(4):515-518
- CountryRepublic of Korea
- Language:English
-
Abstract:
The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis. We have modeled the high wall shear stress (WSS) in a severe M1 stenosis. The high WSS in the systolic phase of the cardiac cycle was well-correlated with a thick fibrous cap atheroma with enhancement, as was determined using high-resolution plaque imaging techniques in a severe stenosis of the middle cerebral artery.
