Contrast study on cognitive function with MRI and positron emission tomography imaging in transient global amnesia.
- Author:
Jianjun JIA
1
;
Luning WANG
;
Ling YIN
;
Hongchuan TANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Amnesia, Transient Global; diagnostic imaging; psychology; Cognition; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Tomography, Emission-Computed
- From: Chinese Medical Journal 2002;115(9):1321-1323
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA).
METHODSThree patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery.
RESULTSNo obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients.
CONCLUSIONSIn TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time.
