Long-term outcome after injection sclerotherapy for esophageal variceal bleeding in children with portal hypertension.
- Author:
Chun-Di XU
1
;
Chao-Hui DENG
;
Yin ZHANG
;
Lin SU
;
Shun-Nian CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Child; Child, Preschool; Duodenal Ulcer; complications; Esophageal and Gastric Varices; etiology; therapy; Esophagoscopy; Gastrointestinal Hemorrhage; etiology; therapy; Humans; Hypertension, Portal; complications; Injections, Intralesional; Polyethylene Glycols; administration & dosage; Recurrence; Reoperation; Sclerosing Solutions; administration & dosage; Sclerotherapy; Time Factors; Treatment Outcome
- From: Chinese Journal of Pediatrics 2004;42(8):574-576
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEEndoscopic sclerotherapy has emerged as an effective treatment for bleeding esophageal varices in adults and children but the long-term outcome is poorly defined in children. The present study aimed to study the long-term effect of endoscopic sclerotherapy in children with portal hypertension.
METHODSFifteen patients (age 3 to 14 years) with esophageal variceal bleeding underwent endoscopic injection treatments with 1% Aethoxy-sclerol since 1996. All subjects continued to receive the therapy by repeated intra and extravariceal endoscopic sclerotherapy at intervals of 3 - 4 weeks until the varices disappeared, and received regular endoscopic follow-up.
RESULTSFifteen patients had totally 43 injections, and were followed up from 40 to 86 months (mean 66 months) by endoscopy. Two patients received 2 injections and 5 received 3 before eradication of varices. The mean time needed for varices eradication was 3 to 6 months. Recurrence of varices and bleeding was seen in 3 patients who had duodenal ulcer.
CONCLUSIONEndoscopic sclerotherapy is a safe and effective treatment for pediatric esophageal varices.
