A Case of Metastatic Gastric Adenocarcinoma Mimicking Preseptal Cellulitis.
- Author:
Kwang Hee WON
1
;
Mi Hye LEE
;
Woo Jin LEE
;
Chong Hyun WON
;
Sung Eun CHANG
;
Jee Ho CHOI
;
Kee Chan MOON
;
Mi Woo LEE
Author Information
- Publication Type:Case Report
- Keywords: Adenocarcinoma; Eyelids; Neoplasm metastasis; Orbital cellulitis
- MeSH: Adenocarcinoma*; Aged; Cellulitis*; Cytoplasm; Dermatitis, Contact; Eyelids; Humans; Immunophenotyping; Keratin-20; Mucin-1; Neoplasm Metastasis; Orbital Cellulitis; Skin; Ulcer
- From:Annals of Dermatology 2015;27(4):439-441
- CountryRepublic of Korea
- Language:English
- Abstract: Cutaneous metastasis from gastric adenocarcinoma is uncommon, and the eyelid is a rare metastatic site. Three patterns of clinical presentation of eyelid metastasis have been described: nodular, infiltrative, and ulcerated. The infiltrative pattern, also known as an inflammatory diffuse pattern or mask-like metastasis, can be easily misdiagnosed as cellulitis or contact dermatitis. Here, we report a case of gastric adenocarcinoma in a 75-year-old man who presented with a localized erythematous plaque on his eyelid that developed four months earlier. The patient had been treated with an antimicrobial agent owing to suspicion of preseptal cellulitis. Gastric adenocarcinoma metastasis was diagnosed on the basis of histopathological examination and immunophenotyping (i.e., cytoplasmic epithelial membrane antigen, cytokeratin- 7, cytokeratin-20, and carcinoembryonic antigen). For patients with malignant neoplasms, persistent skin lesions similar to cellulitis or contact dermatitis should be suspected of metastasis derived from an internal malignancy, even for very rare sites of metastasis.
