Effect of Safflor injection on the intestine ultrastructure characteristics following intestine ischemia/reperfusion injury in rabbits.
- Author:
Hua ZHANG
1
;
Cong-De CHEN
;
Zhong-Rong LI
;
Xiao-Ming CHEN
;
Wan-Tie WANG
;
Wei WANG
;
Fang-Yan WANG
;
Zhou-Xi FANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Carthamus tinctorius; chemistry; Drugs, Chinese Herbal; pharmacology; Female; Intestines; blood supply; ultrastructure; Male; Rabbits; Reperfusion Injury; prevention & control
- From: Chinese Journal of Applied Physiology 2009;25(4):472-475
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo explore effects of Safflor (Chinese Tradional Medicine) on the intestine ultrastructure characteristics during intestine ischemia/ reperfusion injury (I/RI) in rabbits.
METHODSThirty rabbits were randomly divided into three groups: control group (group S), ischemia/reperfusion group (group I/R) and Safflor injection group (group SI). Morphological changes of intestine ischemia/reperfusion in rabbits and the protective effects of Safflor were observed under electric telescope.
RESULTSThe intestine ultrastructure was badly injured in group I/R. Mitochondria and intestinal mucosal cells were swellen and endoplasmic reticulum expanded, however, in the SI group the ultrastructural injury of the ischemia greatly ameliorated.
CONCLUSIONThe ultrastructure injury occurrted after intestine I/RI and Safflor has protective effects on the intestine ultrastructure.
