Study on the relationship between the opacity of lens and the levels of 2, 6-dinitro-4-amino-toluene (DNAT) in the urine of workers exposed to trinitrotoluene(TNT).
- Author:
Zhongde ZHU
1
;
Zhilan LI
;
Fatai MI
;
Suqin LIAN
;
Pengcheng DONG
;
Yuhua WU
;
Xiaohua SUN
Author Information
- Publication Type:Journal Article
- MeSH: Aniline Compounds; urine; Cataract; chemically induced; Environmental Monitoring; Humans; Occupational Exposure; adverse effects; Trinitrotoluene; metabolism
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2002;20(1):42-43
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find out the relationship between the opacity in lens and the contents of 2,6-dinitro-4-amino-toluene(DNAT) in the urine of exposed workers.
METHODSTesting the exposed worker's lens and measuring the contents of DNAT in the urine after work.
RESULTSWhen the opacity of the lens occurred, the contents of DNAT in the urine(2.38 mg/L) of workers exposed to TNT were significantly higher than those without opacity in lens(1.44 mg/L) (P < 0.05).
CONCLUSIONThe severity of opacity of lens increased with the contents of DNAT raised in the urine. The threshold value suggested by ILO is not applicable to Chinese occupational population, which recommends the contents of DNAT(30 mg/L) in the urine for the workers exposed to TNT as biological occupational exposed limits.
